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identifier: 1785574
description:
epitope description:cardiolipin
host organism:Homo sapiens
aggregation:
instance of dataset
availability:
available
primaryPublications: 2730164
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1016314
landingPage: http://www.iedb.org/assay/1785574
type:
Literature
publicationVenue:
Ann Rheum Dis
dates:
1989
study type: b cell assays
subject species:
fullName:
C G Mackworth-Young
S Loizou
M J Walport
method:
ELISA
name:
Primary antiphospholipid syndrome: features of patients with raised anticardiolipin antibodies and no other disorder.
description:
Twenty patients, 18 female and 2 male, were tested for antibodies to cardiolipin. Fourteen patients had raised IgG antibodies, 12 had raised IgM, and six had both. Nine out of 19 had raised antinuclear antibody levels; however, none fulfilled criteria for the diagnosis of SLE. Seven patients had a history of venous thrombosis. Of the 15 female patients who underwent pregnancy, 12 experienced fetal loss. Six individuals had thrombocytopenia and four others had migraines.

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