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Title: Beta2-glycoprotein I is necessary to inhibit protein C activity by monoclonal anticardiolipin antibodies.
identifier: 1787295
description:
epitope description:cardiolipin
host organism:Homo sapiens
antibody name:EY1C8, EY2C9
aggregation:
instance of dataset
availability:
available
primaryPublications: 9920027
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1016223
landingPage: http://www.iedb.org/assay/1787295
type:
Literature
publicationVenue:
Arthritis Rheum
dates:
1999
study type: b cell assays
subject species:
fullName:
M Ieko
K Ichikawa
D A Triplett
E Matsuura
K Sawada
method:
biological activity
name:
Beta2-glycoprotein I is necessary to inhibit protein C activity by monoclonal anticardiolipin antibodies.
description:
The epitope-specific mAbs inhibited activated protein C (APC) activity in the presence of ß2GPI in a concentration-dependent manner as accessed by thrombin generation assay. Without ß2GPI, the APC activity was unaffected by the addition of epitope-specific mAbs.

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