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Title: Epitopes of human chorionic gonadotropin and their relationship to immunogenicity and cross-reactivity of beta-chain mutants.
identifier: 1787299
description:
epitope description:R63
antigen name:Choriogonadotropin subunit beta
host organism:Mus musculus BALB/c
aggregation:
instance of dataset
availability:
available
primaryPublications: 9764366
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1019624
landingPage: http://www.iedb.org/assay/1787299
type:
Literature
publicationVenue:
Am J Reprod Immunol
dates:
1998
study type: b cell assays
subject species: Homo sapiens
fullName:
N Porakishvili
A M Jackson
J B de Souza
M Dalla Chiesa
I M Roitt
P J Delves
method:
ELISA
name:
Epitopes of human chorionic gonadotropin and their relationship to immunogenicity and cross-reactivity of beta-chain mutants.
description:
The epitope was deduced.
Compared to immunization with wildtype ßhCG, immunization with the mutated ßhCG containing the mutation Arg68->Glu resulted in a complete loss of response to ßhCG in 5 of 6 mice, indicating that the epitope is required for immunogenicity.

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