Localization of the receptor binding site of IFN-alpha 2b. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

Localization of the receptor binding site of IFN-alpha 2b.

Dataset

identifier:	1785844
description:	epitope description:R23 antigen name:Interferon alpha-2 host organism:Mus musculus BALB/c antibody name:F2-10, F2-12, F2-13, F2-24
aggregation:	instance of dataset
availability:	available
primaryPublications:	2970505

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1011679
landingPage:	http://www.iedb.org/assay/1785844

Publication

type:	Literature
publicationVenue:	J Immunol
dates:	1988

Dimension

study type:	b cell assays
subject species:	Homo sapiens

Person

fullName:	R Siemers L Hensley H Ozer

Data Type

method:	radio immuno assay (RIA)

Study

name:	Localization of the receptor binding site of IFN-alpha 2b.
description:	The epitope sequence was deduced. The epitope-specific mAb bound to IFN-alpha2b in RIA and EIA. The mAbs did not bind to IFN-alpha2a, which differs from IFN-alpha2b by a single Arg₂₃-Lys₂₃ substitution, indicating that the binding site contains the Arg₂₃ residue.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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