Immunological Data Discovery Index
Immunological Data Discovery Index
| identifier: | 1785952 |
| description: |
epitope description:D36, N37, G40, Y41, S42, N45, G120, N121, K134, G135, T136, D137, V138, Q139, I142, R143
antigen name:Gal d 4
host organism:Mus musculus BALB/c
antibody name:FvD1.3 mutant VL W92F
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| aggregation: |
instance of dataset
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| availability: |
available
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| primaryPublications: |
11112523 |
| authorizations: |
registration not required
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| accessURL: |
http://www.iedb.org/reference/1019319 |
| landingPage: |
http://www.iedb.org/assay/1785952 |
| type: |
Literature
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| publicationVenue: |
Biochemistry
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| dates: |
2000
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| study type: | b cell assays |
| subject species: | Gallus gallus |
| fullName: |
E J Sundberg
M Urrutia
B C Braden
J Isern
D Tsuchiya
B A Fields
E L Malchiodi
J Tormo
F P Schwarz
R A Mariuzza
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| method: |
calorimetry
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| name: |
Estimation of the hydrophobic effect in an antigen-antibody protein-protein interface.
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| description: |
Epitope residues were calculated based on 4Å
atomic distance between the antigen and antibody as in [PDB: 1G7H].
The epitope specific FvD1.3 mutant VL W92F bound to hen egg white lysozyme with a 10-fold reduced affinity compared to wild type FvD1.3 (KA = 5.0 x 107 1/M), as measured by titration calorimetry.
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| name: |
iedb
|
| homePage: |
http://www.iedb.org |
