Immunological Data Discovery Index
Immunological Data Discovery Index
| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1014215 |
| landingPage: |
http://www.iedb.org/assay/1785988 |
| type: |
Literature
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| publicationVenue: |
J Exp Med
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| dates: |
2009
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| study type: | b cell assays |
| subject species: |
| fullName: |
Hü
seyin Uysal
Robert Bockermann
Kutty S Nandakumar
Bettina Sehnert
Estelle Bajtner
Ake Engströ
m
Guy Serre
Harald Burkhardt
Marjolein M G M Thunnissen
Rikard Holmdahl
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| method: |
in vivo assay
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| name: |
Structure and pathogenicity of antibodies specific for citrullinated collagen type II in experimental arthritis.
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| description: |
There was hydroxylation on proline residues 3, 12 and 18 of the epitope.
Adoptive transfer of the epitope specific mAb did not induce arthritis in the mice. However, mAb ACC4 did mediate arthritis relapse in 4of 9 (BALB/c x B10.Q)F1 mice in remission from chronic arthritis induced by injection of collagen II and CFA
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| name: |
iedb
|
| homePage: |
http://www.iedb.org |
