Molecular basis for the preferential cleft recognition by dromedary heavy-chain antibodies. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

Molecular basis for the preferential cleft recognition by dromedary heavy-chain antibodies.

Dataset

identifier:	1786228
description:	epitope description:E53, N62, R63, N64, T65, D66, D70, Q75, V127, A128, R130, N131, R132 antigen name:Gal d 4 host organism:Camelus dromedarius antibody name:D2-L29
aggregation:	instance of dataset
availability:	available
primaryPublications:	16537393

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1019501
landingPage:	http://www.iedb.org/assay/1786228

Publication

type:	Literature
publicationVenue:	Proc Natl Acad Sci U S A
dates:	2006

Dimension

study type:	b cell assays
subject species:	Gallus gallus

Person

fullName:	Erwin De Genst Karen Silence Klaas Decanniere Katja Conrath Remy Loris Jö rg Kinne Serge Muyldermans Lode Wyns

Data Type

method:	surface plasmon resonance (SPR)

Study

name:	Molecular basis for the preferential cleft recognition by dromedary heavy-chain antibodies.
description:	Epitope residues were calculated based on 4Å atomic distance between the antigen and antibody as in [PDB: 1ZV5]. The epitope specific camelid VHH D2-L29 bound to lysozyme.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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