Immunological Data Discovery Index
Immunological Data Discovery Index
| Title: | Clinical importance of persistence of anticardiolipin antibodies in systemic lupus erythematosus. |
| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1016292 |
| landingPage: |
http://www.iedb.org/assay/1786196 |
| type: |
Literature
|
| publicationVenue: |
Ann Rheum Dis
|
| dates: |
1990
|
| study type: | b cell assays |
| subject species: |
| fullName: |
Y Ishii
K Nagasawa
Y Niho
|
| method: |
ELISA
|
| name: |
Clinical importance of persistence of anticardiolipin antibodies in systemic lupus erythematosus.
|
| description: |
Based on the serial measurement of IgG anticardiolipin antibodies, patients could be classified into two groups: group A, persistently positive for IgG anti-cardiolipin antibodies; group B, positive only in the active phases. Of 155 patients, 80 were at the active and 75 at stable stages. The IgG anticardiolipin antibody titer in group A was significantly higher than in group B. The incidence of thromboses, spontaneous abortions, and lupus anticoagulant in group A was significantly higher than in group B (p<005). By contrast, the incidence of renal diseases and anti-dsDNA antibodies in group B was significantly higher than in group A.
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |