Immunological Data Discovery Index
Immunological Data Discovery Index
| identifier: | 1786209 |
| description: |
epitope description:R79, W80, W81, R91, L93, D119, G120, N121, N124, A125, V127, R130, K134
antigen name:Gal d 4
host organism:Camelus dromedarius
antibody name:D2-L19, D2-L29, D2-31, cAbLys2, cAbLys3
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| aggregation: |
instance of dataset
|
| availability: |
available
|
| primaryPublications: |
16537393 |
| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1019501 |
| landingPage: |
http://www.iedb.org/assay/1786209 |
| type: |
Literature
|
| publicationVenue: |
Proc Natl Acad Sci U S A
|
| dates: |
2006
|
| study type: | b cell assays |
| subject species: | Gallus gallus |
| fullName: |
Erwin De Genst
Karen Silence
Klaas Decanniere
Katja Conrath
Remy Loris
Jö
rg Kinne
Serge Muyldermans
Lode Wyns
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| method: |
cross blocking
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| name: |
Molecular basis for the preferential cleft recognition by dromedary heavy-chain antibodies.
|
| description: |
Epitope residues were calculated based on 4Å
atomic distance between the antigen and antibody as in [PDB: 1ZVY].
The epitope specific camelid VHH D3-L11 inhibited the binding by 83-93% of VHHs D2-L19, D2-L29, D2-31, cAbLys2, and cAbLys3 to lysozyme, indicating the antibodies recognized overlapping epitopes.
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |
