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identifier: 1786272
description:
epitope description:cardiolipin
host organism:Homo sapiens
aggregation:
instance of dataset
availability:
available
primaryPublications: 1910214
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1016269
landingPage: http://www.iedb.org/assay/1786272
type:
Literature
publicationVenue:
Thromb Res
dates:
1991
study type: b cell assays
subject species:
fullName:
J J Vogel
G Reber
P de Moerloose
method:
ELISA
name:
Laboratory and clinical features in systemic lupus erythematosus patients with or without anticardiolipin antibodies.
description:
No relationship was found between anti-epitope (aCL) binding levels and activity of the disease and no correlation was observed between aCL positivity and the treatment regimen (steroids, immunosuppressive or antimalarial drugs, oral anticoagulants and aspirin). A statistically significant association was found between the presence of either lupus anticoagulant (LA) or biological false positivity for syphilis (BFP-VDRL) and aCL positivity. The number of arterial complications was statistically higher in aCL-positive patients than in aCL-negative patients.

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