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Title: Synthetic glycopeptide vaccines combining beta-mannan and peptide epitopes induce protection against candidiasis.
identifier: 1787450
description:
epitope description:beta-D-mannopyranosyl-(1->2)-beta-D-mannopyranosyl-(1->2)-beta-D-mannopyranosyl group
antigen name:phosphopeptidomannan
host organism:Mus musculus BALB/c
aggregation:
instance of dataset
availability:
available
primaryPublications: 18725625
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1013478
landingPage: http://www.iedb.org/assay/1787450
type:
Literature
publicationVenue:
Proc Natl Acad Sci U S A
dates:
2008
study type: b cell assays
subject species: Candida albicans
fullName:
Hong Xin
Sebastian Dziadek
David R Bundle
Jim E Cutler
method:
ELISA
name:
Synthetic glycopeptide vaccines combining beta-mannan and peptide epitopes induce protection against candidiasis.
description:
The immunization procedure induced the generation of antibodies against phosphomannoprotein (PMP), composed mainly of phosphomannan, with 10-20% of protein. In mice immunized with the epitope alone, without peptide conjugation, very poor titers were obtained.

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