Immunological Data Discovery Index
Immunological Data Discovery Index
| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1008558 |
| landingPage: |
http://www.iedb.org/assay/1786519 |
| type: |
Literature
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| publicationVenue: |
Vaccine
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| dates: |
1999
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| study type: | b cell assays |
| subject species: | Mus musculus |
| fullName: |
K Sadler
P H Bird
L E Brown
D C Jackson
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| method: |
protection from fertility
|
| name: |
The antigenic and immunogenic properties of synthetic peptide immunocontraceptive vaccine candidates based on gamete antigens.
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| description: |
Mice immunized with the epitope construct exhibited a 59% reduction in birth rate controlled to the control group. Animals with the highest anti-ZP3 titres did not become pregnant. This decrease in birth rate was reversible, when male mice were re-introduced to female mice 24 weeks after the first trial, fertility rates were comparable to the control group.
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| name: |
iedb
|
| homePage: |
http://www.iedb.org |
