| Title: | Strong in vivo maturation compensates for structurally restricted H3 loops in antibody repertoires. |
| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1001552 |
| landingPage: |
http://www.iedb.org/assay/1789617 |
| type: |
Literature
|
| publicationVenue: |
J Biol Chem
|
| dates: |
2005
|
| study type: | b cell assays |
| subject species: | Gallus gallus |
| fullName: |
Erwin De Genst
Karen Silence
Mehdi Arbabi Ghahroudi
Klaas Decanniere
Remy Loris
Jö
rg Kinne
Lode Wyns
Serge Muyldermans
|
| method: |
surface plasmon resonance (SPR)
|
| name: |
Strong in vivo maturation compensates for structurally restricted H3 loops in antibody repertoires.
|
| description: |
Epitope residues are calculated from [PDB: 1RI8] at 4Å
atomic distance from the antibody.
Epitope-specific VHH D2-L19 bound to hen egg white lysozyme with a typical value for an affinity-matured antibody.
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |