Role of beta 2-glycoprotein I in the antiphospholipid antibody binding to endothelial cells. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

Role of beta 2-glycoprotein I in the antiphospholipid antibody binding to endothelial cells.

Dataset

identifier:	1788471
description:	epitope description:cardiolipin host organism:Homo sapiens
aggregation:	instance of dataset
availability:	available
primaryPublications:	7655487

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1016243
landingPage:	http://www.iedb.org/assay/1788471

Publication

type:	Literature
publicationVenue:	Lupus
dates:	1995

Dimension

study type:	b cell assays
subject species:

Person

fullName:	M Le Tonquè ze K Salozhin M Dueymes J C Piette V Kovalev Y Shoenfeld E Nassonov P Youinou

Data Type

method:	ELISA

Study

name:	Role of beta 2-glycoprotein I in the antiphospholipid antibody binding to endothelial cells.
description:	Binding to the epitope was inhibited by pre-absorbing the sera with endothelial cells. ß₂GPI may mediate anticardiolipin binding to endothelial cells, based on the increased binding of affinity purified anticardiolipin antibodies in the presence of added ß₂GPI.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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