Cross-reactivity between the mannan of Candida species, Klebsiella K24 polysaccharide and Salmonella C1 and E O-antigens is mediated by a terminal non-reducing beta-mannosyl residue.

Title:

Cross-reactivity between the mannan of Candida species, Klebsiella K24 polysaccharide and Salmonella C1 and E O-antigens is mediated by a terminal non-reducing beta-mannosyl residue.

Dataset

identifier:	1788695
description:	epitope description:beta-D-mannose antigen name:lipopolysaccharide host organism:Rattus norvegicus LOU/C antibody name:MASC1-MR9
aggregation:	instance of dataset
availability:	available
primaryPublications:	7511532

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1008776
landingPage:	http://www.iedb.org/assay/1788695

Publication

type:	Literature
publicationVenue:	Eur J Biochem
dates:	1994

Dimension

study type:	b cell assays
subject species:	Salmonella thompson C1 strain IS40

Person

fullName:	N A Nnalue A Weintraub S Oscarson A A Lindberg

Data Type

method:	antigen inhibition (~ IC50)

Study

name:	Cross-reactivity between the mannan of Candida species, Klebsiella K24 polysaccharide and Salmonella C1 and E O-antigens is mediated by a terminal non-reducing beta-mannosyl residue.
description:	The epitope inhibited binding of the epitope specific monoclonal antibody to mannan or glycoconjugate specific for Salmonella serogroup C₁ or E. IC₅₀ for inhibition of binding to mannan was 11101 nM, 44406 nM for inhibition of binding to serogroup E glycoconjugate and 9436 nM for inhibition of binding to serogroup C₁ glycoconjugate.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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