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identifier: 1471289
description:
epitope description:YFDGRGRAESIRMTLVAAGVDYEDERISFQDWPK
antigen name:Glutathione S-transferase class-mu 28 kDa isozyme
host organism:Homo sapiens
aggregation:
instance of dataset
availability:
available
primaryPublications: 10823801
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1006299
landingPage: http://www.iedb.org/assay/1471289
type:
Literature
publicationVenue:
J Infect Dis
dates:
2000
study type: b cell assays
subject species: Schistosoma mansoni
fullName:
F Remoué
F Rogerie
M C Gallissot
H L Guyatt
J L Neyrinck
M M Diakkhate
M Niang
A E Butterworth
C Auriault
A Capron
G Riveau
method:
ELISA
name:
Sex-dependent neutralizing humoral response to Schistosoma mansoni 28GST antigen in infected human populations.
description:
The epitope sequence is published in Xu et al. J Immunol. 1993 Feb 1
150(3):940-9.PMID: 8423348.
Isotypic humoral responses to the peptide were studied according to sex. In males showing a low intensity of infection, only the mean IgG3 response against the epitope was stronger than that observed in the high-intensity infection group. However, this finding and the correlation withSchistosoma mansoni 28-kDa GST enzymtic inhibition were not statistically significant. No differences were observed in the levels of IgG3 response to the epitope in the female population.

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