Recognition of B and T cell epitopes by cattle immunized with a synthetic peptide containing the major immunogenic site of VP1 FMDV 01 Campos.

Title:

Recognition of B and T cell epitopes by cattle immunized with a synthetic peptide containing the major immunogenic site of VP1 FMDV 01 Campos.

identifier:	1472236
description:	epitope description:RYSRNAVPNV antigen name:Polyprotein host organism:Bos taurus antibody name:Cattle immunoglobulin
aggregation:	instance of dataset
availability:	available
primaryPublications:	8184548

study type:	b cell assays
subject species:	Foot-and-mouth disease virus (strain O1) (O1 Campos)

fullName:	P Zamorano A Wigdorovitz M T Chaher F M Fernandez C Carrillo F E Marcovecchio A M Sadir M V Borca

method:	biological activity

name:	Recognition of B and T cell epitopes by cattle immunized with a synthetic peptide containing the major immunogenic site of VP1 FMDV 01 Campos.
description:	The paper refers to the sequence of the VP1 protein which is processed from the larger polyprotein referenced in the database. The protein G-purified immunoglobulin against the larger peptide VP1 aa 135-160 was further affinity purified against this epitope. Immunoglobulin specific for this epitope was then used in a neutralization assay and showed a clear neutralizing Ab response..

name:	iedb
homePage:	http://www.iedb.org

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