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identifier: 1472509
description:
epitope description:RSDYKFYEDANGTRDHKKG
antigen name:Outer membrane protein A (3aII*Gd)
host organism:Chinchilla lanigera
antibody name:chinchilla antisera
aggregation:
instance of dataset
availability:
available
primaryPublications: 9261941
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1006111
landingPage: http://www.iedb.org/assay/1472509
type:
Literature
publicationVenue:
Vaccine
dates:
1997
study type: b cell assays
subject species: Haemophilus influenzae NTHi 1128
fullName:
L O Bakaletz
E R Leake
J M Billy
P T Kaumaya
method:
ELISA
name:
Relative immunogenicity and efficacy of two synthetic chimeric peptides of fimbrin as vaccinogens against nasopharyngeal colonization by nontypeable Haemophilus influenzae in the chinchilla.
description:
Another fimbrin peptide (YQWLTRVGKYRPQDKPNT), also possessing a carrier moiety (Measles Virus T-cell epitope), was recognized by antiserum from immunized animals, but to a much lesser degree. Because this peptide shared no sequence with the LB1 epitope, recognition likely was due to the generation of antibodies specific for the common carrier region. Additionally, Western Blot analysis revealed that antisera from immunized animals recognized the epitope, but not the other fimbrin peptide. .

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