Relative immunogenicity and efficacy of two synthetic chimeric peptides of fimbrin as vaccinogens against nasopharyngeal colonization by nontypeable Haemophilus influenzae in the chinchilla.

Title:

Relative immunogenicity and efficacy of two synthetic chimeric peptides of fimbrin as vaccinogens against nasopharyngeal colonization by nontypeable Haemophilus influenzae in the chinchilla.

Dataset

identifier:	1472524
description:	epitope description:RSDYKFYEDANGTRDHKKG antigen name:Outer membrane protein A (3aII*Gd) host organism:Chinchilla lanigera antibody name:chinchilla antisera
aggregation:	instance of dataset
availability:	available
primaryPublications:	9261941

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1006111
landingPage:	http://www.iedb.org/assay/1472524

Publication

type:	Literature
publicationVenue:	Vaccine
dates:	1997

Dimension

study type:	b cell assays
subject species:	Haemophilus influenzae NTHi 1128

Person

fullName:	L O Bakaletz E R Leake J M Billy P T Kaumaya

Data Type

method:	in vivo assay

Study

name:	Relative immunogenicity and efficacy of two synthetic chimeric peptides of fimbrin as vaccinogens against nasopharyngeal colonization by nontypeable Haemophilus influenzae in the chinchilla.
description:	Immunized animals were able to clear bacteria from nasopharyngeal colonization 21 days after challenge (with either 5x10^7 or 1.5x10^8 CFU).

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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