Conjugates of synthetic cyclic peptides elicit bactericidal antibodies against a conformational epitope on a class 1 outer membrane protein of Neisseria meningitidis.

Title:

Conjugates of synthetic cyclic peptides elicit bactericidal antibodies against a conformational epitope on a class 1 outer membrane protein of Neisseria meningitidis.

Dataset

identifier:	1472986
description:	epitope description:YTKDTNNNL antigen name:Major outer membrane protein P.IA host organism:Mus musculus BALB/c antibody name:Mouse sera
aggregation:	instance of dataset
availability:	available
primaryPublications:	7543883

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1007414
landingPage:	http://www.iedb.org/assay/1472986

Publication

type:	Literature
publicationVenue:	Infect Immun
dates:	1995

Dimension

study type:	b cell assays
subject species:	Neisseria meningitidis serogroup B H44/76

Person

fullName:	P Hoogerhout E M Donders J A van Gaans-van den Brink B Kuipers H F Brugghe L M van Unen H A Timmermans G J ten Hove A P de Jong C C Peeters

Data Type

method:	ELISA

Study

name:	Conjugates of synthetic cyclic peptides elicit bactericidal antibodies against a conformational epitope on a class 1 outer membrane protein of Neisseria meningitidis.
description:	The epitope is cyclized. Amino acid positions differ because the database sequence includes the signal polypeptide. Significant reactivity to whole bacteria was not generated using either adjuvant.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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