Molecular cloning and epitope analysis of the peanut allergen Ara h 3. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

Molecular cloning and epitope analysis of the peanut allergen Ara h 3.

Dataset

identifier:	1475987
description:	epitope description:DEDEYEYDEEDRRRG antigen name:Ara h 3 host organism:Homo sapiens antibody name:human sera
aggregation:	instance of dataset
availability:	available
primaryPublications:	10021462

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/315295
landingPage:	http://www.iedb.org/assay/1475987

Publication

type:	Literature
publicationVenue:	J Clin Invest
dates:	1999

Dimension

study type:	b cell assays
subject species:	Arachis hypogaea

Person

fullName:	P Rabjohn E M Helm J S Stanley C M West H A Sampson A W Burks G A Bannon

Data Type

method:	western blot

Study

name:	Molecular cloning and epitope analysis of the peanut allergen Ara h 3.
description:	Data originally imported from the Database of Functional Molecular Immunology, FIMM (http://sdmc.lit.org.sg:8080/fimm/) and recurated. The following refers to the epitope id as found in the original FIMM database: P001793 The epitope sequence was deduced through study of overlapping peptides spanning the sequence of Ara h 3. Single amino acid alanine substitutions established Glu residues at positions 6, 9 and 10, Tyr at position 7, Asp at position 8, and Arg at position 12 to be critical for IgE binding. The core epitope was determined to be YEYDEEDRR.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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