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identifier: 1474281
description:
epitope description:NSGCFRHLDEREECKCLL
antigen name:Merozoite surface protein 1
host organism:Homo sapiens
antibody name:Human sera
aggregation:
instance of dataset
availability:
available
primaryPublications: 18086262
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1007760
landingPage: http://www.iedb.org/assay/1474281
type:
Literature
publicationVenue:
Scand J Immunol
dates:
2008
study type: b cell assays
subject species: Plasmodium falciparum Mad20/Papua New Guinea
fullName:
S Biswas
R K Seth
P K Tyagi
S K Sharma
A P Dash
method:
ELISA
name:
Naturally acquired immunity and reduced susceptibility to falciparum malaria in two subpopulations of endemic eastern India.
description:
Overall higher antibody titers were observed in the PT population compared to the KF population. There was an age-wise increasing trend in antibody prevalence in both areas. While responses were similar in the adults from each area (98 and 96%, respectively), the response in the two groups of children were much higher in the PT area (80% and 95% PT compared to 45% and 76% KF). The differences were associated with differences in endemicity. Responses to the MSP-1 epitope were highest. There was also a significant association between sero-positivity and parasite positivity among all subjects.

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