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identifier: 1474974
description:
epitope description:VAQYKALPVVLENA
antigen name:Fel d 1
host organism:Homo sapiens
antibody name:patient sera
aggregation:
instance of dataset
availability:
available
primaryPublications: 7508463
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/315027
landingPage: http://www.iedb.org/assay/1474974
type:
Literature
publicationVenue:
J Allergy Clin Immunol
dates:
1994
study type: b cell assays
subject species: Felis catus
fullName:
F J van Milligen
W van 't Hof
M van den Berg
R C Aalberse
method:
antigen inhibition
name:
IgE epitopes on the cat (Felis domesticus) major allergen Fel d I: a study with overlapping synthetic peptides.
description:
Data originally imported from the Database of Functional Molecular Immunology, FIMM (http://sdmc.lit.org.sg:8080/fimm/) and recurated. The following refers to the epitope id as found in the original FIMM database: P001838
Preincubation of cat-allergic patient serum IgE with cat dander extract, affinity-purified Fel d I, or reduced and alkylated Fel d I inhibited binding to the epitope in a dose-dependent manner. The epitope was synthesized with an additional C-terminal lysine residues for coupling to Sepharose.

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