Immunological Data Discovery Index
Immunological Data Discovery Index
| authorizations: |
registration not required
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| accessURL: |
http://www.iedb.org/reference/1006735 |
| landingPage: |
http://www.iedb.org/assay/1475511 |
| type: |
Literature
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| publicationVenue: |
J Virol
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| dates: |
1994
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| study type: | b cell assays |
| subject species: | Theiler's encephalomyelitis virus (STRAIN BEAN 8386) |
| fullName: |
A Inoue
Y K Choe
B S Kim
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| method: |
western blot
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| name: |
Analysis of antibody responses to predominant linear epitopes of Theiler's murine encephalomyelitis virus.
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| description: |
The amino acid positions from the paper refer to the mature VP1 protein, which is processed from the polyprotein that is represented in the database.
Sera from SLJ/J mice intracerebrally infected with TMEV reacted strongly with this epitope in immunoblots and in ELISA assays. In intracerebrally infected SLJ/J mice, which are highly susceptible to TMEV, only reactivity to this B-cell epitope was seen, though sera from mice immunized with UV-inactivated TMEV, who did not develop infection, did have reactivity to other epitopes. Anti-epitope antibody in intracerebrally infected mice was of subclasses IgG1, IgG2a, and IgG2b.
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| name: |
iedb
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| homePage: |
http://www.iedb.org |
