The fourth surface-exposed region of the outer membrane protein P5-homologous adhesin of nontypable Haemophilus influenzae is an immunodominant but nonprotective decoying epitope.

Title:

The fourth surface-exposed region of the outer membrane protein P5-homologous adhesin of nontypable Haemophilus influenzae is an immunodominant but nonprotective decoying epitope.

Dataset

identifier:	1476786
description:	epitope description:TRVGKYRPQDKPNTAINYNPWIG antigen name:Outer membrane protein A (3aII*Gd) host organism:Chinchilla lanigera antibody name:Convalescent chinchilla sera
aggregation:	instance of dataset
availability:	available
primaryPublications:	12902501

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1006363
landingPage:	http://www.iedb.org/assay/1476786

Publication

type:	Literature
publicationVenue:	J Immunol
dates:	2003

Dimension

study type:	b cell assays
subject species:	Haemophilus influenzae NTHi 1128

Person

fullName:	Laura A Novotny Lauren O Bakaletz

Data Type

method:	surface plasmon resonance (SPR)

Study

name:	The fourth surface-exposed region of the outer membrane protein P5-homologous adhesin of nontypable Haemophilus influenzae is an immunodominant but nonprotective decoying epitope.
description:	The epitope sequence is provided in Novotny et al. (2000) [PMID:10722609]. Serum from all of seven experimentally infected chinchillas taken 35 days after infection, when otitis media had resolved, reacted to this epitope in an SPR assay.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

Feedback?

If you are having problems using our tools, or if you would just like to send us some feedback, please post your questions on Feedback.