Beta-PrP form of human prion protein stimulates production of monoclonal antibodies to epitope 91-110 that recognise native PrPSc.

Title:

Beta-PrP form of human prion protein stimulates production of monoclonal antibodies to epitope 91-110 that recognise native PrPSc.

identifier:	1477628
description:	epitope description:GSAMSRPIIHFGSDYEDRYY antigen name:Major prion protein host organism:Mus musculus PrP null antibody name:ICSM17
aggregation:	instance of dataset
availability:	available
primaryPublications:	17936697

study type:	b cell assays
subject species:	Homo sapiens

fullName:	Azadeh Khalili-Shirazi Maria Kaisar Gary Mallinson Samantha Jones Daljit Bhelt Carol Fraser Anthony R Clarke Simon H Hawke Graham S Jackson John Collinge

method:	flow cytometry

name:	Beta-PrP form of human prion protein stimulates production of monoclonal antibodies to epitope 91-110 that recognise native PrPSc.
description:	The sequence is from the reference cited: Zahn et al. (2000) Proc. Natl. Acad. Sci. U.S.A. 97:145-150. [PMID: 10618385] The epitope-specific mAb reacted with human native PrP^c expressed on U937 cells.

name:	iedb
homePage:	http://www.iedb.org

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