Vaccine-induced IgG antibodies to the linear epitope on the PorB outer membrane protein promote opsonophagocytosis of Neisseria meningitidis by human neutrophils.

Title:

Vaccine-induced IgG antibodies to the linear epitope on the PorB outer membrane protein promote opsonophagocytosis of Neisseria meningitidis by human neutrophils.

Dataset

identifier:	1478082
description:	epitope description:VETSRSVFHQNGQVTEVTTATGI antigen name:Major outer membrane protein P.IB host organism:Homo sapiens antibody name:peptide D63b2-specific IgG preparation
aggregation:	instance of dataset
availability:	available
primaryPublications:	9191881

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1008400
landingPage:	http://www.iedb.org/assay/1478082

Publication

type:	Literature
publicationVenue:	Clin Immunol Immunopathol
dates:	1997

Dimension

study type:	b cell assays
subject species:	Neisseria meningitidis serogroup B H44/76

Person

fullName:	A A Delvig T E Michaelsen A Aase E A Hoiby E Rosenqvist

Data Type

method:	ELISA

Study

name:	Vaccine-induced IgG antibodies to the linear epitope on the PorB outer membrane protein promote opsonophagocytosis of Neisseria meningitidis by human neutrophils.
description:	Antibodies (IgG1) specific to the epitope were affinity-purified from a vaccinee serum; this preparation recognized Neisseria meningitidis strain 44/76 by ELISA. Affinity measurements were also done by ELISA for this IgG1 preparation.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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