Immunological Data Discovery Index
Advanced Search
identifier: 1478007
description:
epitope description:G106
antigen name:Genome polyprotein
host organism:Mus musculus
antibody name:4A1B-9
aggregation:
instance of dataset
availability:
available
primaryPublications: 17374760
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1007684
landingPage: http://www.iedb.org/assay/1478007
type:
Literature
publicationVenue:
J Gen Virol
dates:
2007
study type: b cell assays
subject species: West Nile virus
fullName:
Wayne D Crill
Nicole B Trainor
Gwong-Jen J Chang
method:
ELISA
name:
A detailed mutagenesis study of flavivirus cross-reactive epitopes using West Nile virus-like particles.
description:
Residue G106 was determined to be an epitopic determinant for flavivirus group cross-reactive mAb 4A1B-9 by binding analyses to mutants of WNV E protein. Mutations G106V, G106R, and G106Y abolished binding, whereas mutation G106A reduced binding.

Feedback?

If you are having problems using our tools, or if you would just like to send us some feedback, please post your questions on Feedback.