Establishment of hybrid cell lines producing monoclonal antibodies to a synthetic peptide from the E1 region of the hepatitis C virus.

Title:

Establishment of hybrid cell lines producing monoclonal antibodies to a synthetic peptide from the E1 region of the hepatitis C virus.

identifier:	1478125
description:	epitope description:GHRMAWDMM antigen name:Genome polyprotein host organism:Mus musculus BALB/c antibody name:10C7 and 10B2
aggregation:	instance of dataset
availability:	available
primaryPublications:	18080883

study type:	b cell assays
subject species:	Hepatitis C virus

fullName:	Ashraf A Tabll Samy B Khalil Reem M El-Shenawy Gamal Esmat Amr Helmy Abdel Fattah Attallah Mostafa K El-Awady

method:	ELISA

name:	Establishment of hybrid cell lines producing monoclonal antibodies to a synthetic peptide from the E1 region of the hepatitis C virus.
description:	Monoclonal antibody 10C7 was characterized as IgG2b, and 10B2 was identified as IgG1. Epitope-specific mAbs recognized HCV E1 protein in sera collected from HCV infected Egyptian patients. In a separate experiment, results were corroborated by Western/Immunoblot screening of patients' sera.

name:	iedb
homePage:	http://www.iedb.org

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