A monoclonal antibody (1D12) defines novel distribution patterns of prion protein (PrP) as granules in nucleus.

Title:

A monoclonal antibody (1D12) defines novel distribution patterns of prion protein (PrP) as granules in nucleus.

identifier:	1478150
description:	epitope description:RPMIHF antigen name:Major prion protein host organism:Mus musculus PrP null antibody name:T2
aggregation:	instance of dataset
availability:	available
primaryPublications:	18068119

study type:	b cell assays
subject species:	Mus musculus

fullName:	Tomoko Hosokawa Kotaro Tsuchiya Ichiro Sato Natsumi Takeyama Susumu Ueda Yuichi Tagawa Kumiko M Kimura Izuru Nakamura Guoying Wu Akikazu Sakudo Cristina Casalone Maria Mazza Maria Caramelli Hidehiro Takahashi Tetsutaro Sata Katsuaki Sugiura Andreina Baj Antonio Toniolo Takashi Onodera

method:	immuno staining

name:	A monoclonal antibody (1D12) defines novel distribution patterns of prion protein (PrP) as granules in nucleus.
description:	The sequence is from the reference cited: Hayashi et al. (2004) J Vet Med Sci 66: 515-520. [PMID: 15187361] The epitope-specific mAb recognized bovine PrP^C transfected into NpL2 (Prnp^-/-) cells, with immunoreactivity mainly in the cell membrane.

name:	iedb
homePage:	http://www.iedb.org

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