Identification of neutralizing epitopes on the VP2 protein of infectious bursal disease virus by phage-displayed heptapeptide library screening and synthetic peptide mapping.

Title:

Identification of neutralizing epitopes on the VP2 protein of infectious bursal disease virus by phage-displayed heptapeptide library screening and synthetic peptide mapping.

Dataset

identifier:	1479011
description:	epitope description:ARGSLAVTI antigen name:Structural polyprotein host organism:Mus musculus antibody name:YNW29
aggregation:	instance of dataset
availability:	available
primaryPublications:	16212534

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1009103
landingPage:	http://www.iedb.org/assay/1479011

Publication

type:	Literature
publicationVenue:	Viral Immunol
dates:	2005

Dimension

study type:	b cell assays
subject species:	Infectious bursal disease virus

Person

fullName:	Xuan-Nian Wang Gai-Ping Zhang Ji-Yong Zhou Chun-Hua Feng Yan-Yan Yang Qing-Mei Li Jun-Qing Guo Hong-Xing Qiao Jun Xi Dong Zhao Guang Xu Xing Zi-Liang Wang San-Hu Wang Zhi-Jun Xiao Xue-Wu Li Rui-Guang Deng

Data Type

method:	antigen inhibition

Study

name:	Identification of neutralizing epitopes on the VP2 protein of infectious bursal disease virus by phage-displayed heptapeptide library screening and synthetic peptide mapping.
description:	The epitope was able to compete for binding of the mAb to VP2. The epitope was shown to bind to the mAb by ELISA using overlapping peptides. Phage clones were selected from a phage display library with the mAb, and all had the motif ARG.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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