Effect of adjuvant composition on immune response to a multiple antigen peptide (MAP) containing a protective epitope from Neisseria meningitidis class 1 porin.

Title:

Effect of adjuvant composition on immune response to a multiple antigen peptide (MAP) containing a protective epitope from Neisseria meningitidis class 1 porin.

Dataset

identifier:	1479326
description:	epitope description:TKNTNNNLTL antigen name:Major outer membrane protein P.IA host organism:Mus musculus BALB/c antibody name:mouse serum
aggregation:	instance of dataset
availability:	available
primaryPublications:	10501243

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1008917
landingPage:	http://www.iedb.org/assay/1479326

Publication

type:	Literature
publicationVenue:	Vaccine
dates:	1999

Dimension

study type:	b cell assays
subject species:	Neisseria meningitidis

Person

fullName:	M Christodoulides E Rattue J E Heckels

Data Type

method:	surface plasmon resonance (SPR)

Study

name:	Effect of adjuvant composition on immune response to a multiple antigen peptide (MAP) containing a protective epitope from Neisseria meningitidis class 1 porin.
description:	Additional adjuvants were used for immunization, including Quil A, calcium phosphate, alum, Freund's, Ribi, and a water-in-oil emulsion of pluronic-muramyl dipeptide-monophosphoryl lipid, but yielded higher dissociation rate constants for epitope-specific antibodies. Epitope coupled to T helper epitope from tetanus toxin in a multi-epitope construct was also recognized by antisera.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

Feedback?

If you are having problems using our tools, or if you would just like to send us some feedback, please post your questions on Feedback.