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identifier: 1479342
description:
epitope description:AAAGFMVLQDINCFRPHGVSAAQEKISFGKSSQCREAVGT
antigen name:Glycoprotein 4
host organism:Mus musculus
antibody name:121.4, 122.1, 122.20, 122.59, 122.68, 122.70, 126.1, 126.7,122.29, 122.30, 122.66, 122.71, 130.7, 138.28, 122.12
aggregation:
instance of dataset
availability:
available
primaryPublications: 9223499
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1009733
landingPage: http://www.iedb.org/assay/1479342
type:
Literature
publicationVenue:
J Virol
dates:
1997
study type: b cell assays
subject species: Lelystad virus
fullName:
J J Meulenberg
A P van Nieuwstadt
A van Essen-Zandbergen
J P Langeveld
method:
ELISA
name:
Posttranslational processing and identification of a neutralization domain of the GP4 protein encoded by ORF4 of Lelystad virus.
description:
The epitope sequence recognized by 15 mAbs was deduced through study of chimeric GP4 protein of LV and the US isolate VR2332 transfected into BHK-21 cells. The mAbs recognized constructs containing the epitope residues 40-79 of LV fused to residues 1-39 and 76-178 of VR2332 GP4, but did not recognize VR2332 GP4. The mAbs recognized LV GP4 protein in Western blots.

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