Antibody responses are generated to immunodominant ELK/KLE-type motifs on the nonstructural-1 glycoprotein during live dengue virus infections in mice and humans: implications for diagnosis, pathogenesis, and vaccine design.

Title:

Dataset

identifier:	1480266
description:	epitope description:ELRYSWKTWGKAKMLSTELH antigen name:Genome polyprotein host organism:Mus musculus BALB/c antibody name:1A12.3, 3D1.4, 4H3.4, 3A5.4, 1G5.4-A1-C3
aggregation:	instance of dataset
availability:	available
primaryPublications:	17329445

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1006742
landingPage:	http://www.iedb.org/assay/1480266

Publication

type:	Literature
publicationVenue:	Clin Vaccine Immunol
dates:	2007

Dimension

study type:	b cell assays
subject species:	Dengue virus 2 Puerto Rico/PR159-S1/1969

Person

fullName:	Andrew K I Falconar

Data Type

method:	ELISA

Study

name:	Antibody responses are generated to immunodominant ELK/KLE-type motifs on the nonstructural-1 glycoprotein during live dengue virus infections in mice and humans: implications for diagnosis, pathogenesis, and vaccine design.
description:	This epitope was synthesized with a C-terminal Cys residue. MAbs 1A12.3, 3D1.4, 4H3.4, 3A5.4, 1G5.4-A1-C3, which all recognize the LX1 peptide YSWKTWGKA within the epitope sequence, reacted with the epitope by ELISA and Western blotting.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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