Rapid identification of malaria vaccine candidates based on alpha-helical coiled coil protein motif.

Title:

Rapid identification of malaria vaccine candidates based on alpha-helical coiled coil protein motif.

identifier:	1480818
description:	epitope description:GGLKNSNHNLNNIEMKYNTLNNNMNSINK antigen name:Uncharacterized protein MAL13P1.304 host organism:Homo sapiens
aggregation:	instance of dataset
availability:	available
primaryPublications:	17653272

study type:	b cell assays
subject species:	Plasmodium falciparum 3D7

fullName:	Viviane Villard George W Agak Gé raldine Frank Ali Jafarshad Catherine Servis Issa Né bié Sodiomon B Sirima Ingrid Felger Myriam Arevalo-Herrera Socrates Herrera Frederic Heitz Volker Bä cker Pierre Druilhe Andrey V Kajava Giampietro Corradin

method:	biological activity

name:	Rapid identification of malaria vaccine candidates based on alpha-helical coiled coil protein motif.
description:	Sera from immune African adults were affinity purified using the epitope. These antibodies were then tested for the ability to inhibit the growth of the parasite in ADCI assay. In a separate peptide inhibition assay, the authors demonstrated the specificity of the antibodies to the epitope.

name:	iedb
homePage:	http://www.iedb.org

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