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Title: Small peptides induce antibodies with a sequence and structural requirement for binding antigen comparable to antibodies raised against the native protein.
identifier: 1480903
description:
epitope description:GDLGSIA
antigen name:Genome polyprotein
host organism:Oryctolagus cuniculus
antibody name:anti-VP1 Peptide type A10
aggregation:
instance of dataset
availability:
available
primaryPublications: 2578661
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1008339
landingPage: http://www.iedb.org/assay/1480903
type:
Literature
publicationVenue:
Proc Natl Acad Sci U S A
dates:
1985
study type: b cell assays
subject species: Foot-and-mouth disease virus (strain A10-61)
fullName:
H M Geysen
S J Barteling
R H Meloen
method:
ELISA
name:
Small peptides induce antibodies with a sequence and structural requirement for binding antigen comparable to antibodies raised against the native protein.
description:
The epitope was synthesized with an N-terminal Cys and a C-terminal Lys residue.
Sera from rabbits immunized with the epitope reacted with the virus in an ELISA but were negative in a virus neutralization test. The antisera did not cross-react with FMDV type O1 or FMDV type C1.

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