A peptide mimic of a protective epitope of respiratory syncytial virus selected from a combinatorial library induces virus-neutralizing antibodies and reduces viral load in vivo.

Title:

A peptide mimic of a protective epitope of respiratory syncytial virus selected from a combinatorial library induces virus-neutralizing antibodies and reduces viral load in vivo.

Dataset

identifier:	1483097
description:	epitope description:HWSISKPQ host organism:Mus musculus BALB/c
aggregation:	instance of dataset
availability:	available
primaryPublications:	9499058

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1006619
landingPage:	http://www.iedb.org/assay/1483097

Publication

type:	Literature
publicationVenue:	J Virol
dates:	1998

Dimension

study type:	b cell assays
subject species:

Person

fullName:	D Chargelegue O E Obeid S C Hsu M D Shaw A N Denbury G M W Steward

Data Type

method:	ELISA

Study

name:	A peptide mimic of a protective epitope of respiratory syncytial virus selected from a combinatorial library induces virus-neutralizing antibodies and reduces viral load in vivo.
description:	Anti-sera to a MAP construct composed of 4 copies of the epitope bound RSV A2 by ELISA. A mAb to the epitope was able to inhibit the binding of the anti-sera to RSV. Similar results were seen with the administration of a MAP that also contained a T helper epitope from measles virus.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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