Peptide mimotopes as prototypic templates of broad-spectrum surrogates of carbohydrate antigens. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

Peptide mimotopes as prototypic templates of broad-spectrum surrogates of carbohydrate antigens.

Dataset

identifier:	1483034
description:	epitope description:GGIYYPYDIYYPYDIYYPYD host organism:Mus musculus
aggregation:	instance of dataset
availability:	available
primaryPublications:	12887105

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1012089
landingPage:	http://www.iedb.org/assay/1483034

Publication

type:	Literature
publicationVenue:	Cell Mol Biol (Noisy-le-grand)
dates:	2003

Dimension

study type:	b cell assays
subject species:

Person

fullName:	G Cunto-Amesty P Luo B Monzavi-Karbassi A Lees J Alexander M F del Guercio M H Nahm C Artaud J Stanley

Data Type

method:	antigen inhibition

Study

name:	Peptide mimotopes as prototypic templates of broad-spectrum surrogates of carbohydrate antigens.
description:	The eptiope (in conjugated multiple antigen peptide form) competed with pneumococcal capsular polysaccharide type 14 (Pn14) for binding to the mAb. Substitution of P6, P12, and P18 with Arg or Y5, Y11, and Y17 with Trp drastically reduced antibody binding.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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