An epitope located at the C terminus of isolated VP1 of foot-and-mouth disease virus type O induces neutralizing activity but poor protection.

Title:

An epitope located at the C terminus of isolated VP1 of foot-and-mouth disease virus type O induces neutralizing activity but poor protection.

identifier:	1481882
description:	epitope description:GDLQVLA antigen name:Polyprotein host organism:Oryctolagus cuniculus antibody name:anti-146-152
aggregation:	instance of dataset
availability:	available
primaryPublications:	2418152

study type:	b cell assays
subject species:	Foot-and-mouth disease virus (strain O1)

fullName:	R H Meloen S J Barteling

method:	radio immuno assay (RIA)

name:	An epitope located at the C terminus of isolated VP1 of foot-and-mouth disease virus type O induces neutralizing activity but poor protection.
description:	The sequence is from the reference cited: Geysen et al. (1985) Proc Natl Acad Sci USA 82: 178-182. [PMID: 2578661] Anti-146-152 peptide antiserum reacted with 140S virus particles by RIA. The antiserum did not react with trypsin-treated virus, which removes VP1 residues 136-158 and 199-213. The antiserum did not neutralize the virus.

name:	iedb
homePage:	http://www.iedb.org

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