Epitope mapping of foot-and-mouth disease virus with neutralizing monoclonal antibodies. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

Epitope mapping of foot-and-mouth disease virus with neutralizing monoclonal antibodies.

Dataset

identifier:	1481980
description:	epitope description:SKYSAGGTGRRGDLGPLAARVAAQLP antigen name:Polyprotein host organism:Cavia porcellus Duncan-Hartley antibody name:anti-Peptide 135-160Cys
aggregation:	instance of dataset
availability:	available
primaryPublications:	2471783

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1011080
landingPage:	http://www.iedb.org/assay/1481980

Publication

type:	Literature
publicationVenue:	J Gen Virol
dates:	1989

Dimension

study type:	b cell assays
subject species:	Foot-and-mouth disease virus - type A (strain A22 Iraq)

Person

fullName:	C Bolwell B E Clarke N R Parry E J Ouldridge F Brown D J Rowlands

Data Type

method:	biological activity

Study

name:	Epitope mapping of foot-and-mouth disease virus with neutralizing monoclonal antibodies.
description:	The epitope was synthesized with a C-termianl Cys residue. Anti-Peptide 135-160Cys antiserum neutralized a wide range of serotype A viruses, including FMDV strain A22 Iraq 24/64 (monolayer-adapted clone 162-154 and suspension cell-adapted clone 148-173), A Jordan 8/78, A Burma 6/78, A Bangladesh 8/78, and A Saudi Arabia 19/84, but not A Pakistan 7/80.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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