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Title: Location of neutralizing epitopes defined by monoclonal antibodies generated against the outer capsid polypeptide, VP1, of foot-and-mouth disease virus A12.
identifier: 1482481
description:
epitope description:GDFGSLAPRVARQLPASFNYGAIK
antigen name:Genome polyprotein
host organism:Mus musculus BALB/c
antibody name:6HE4, 7SF3
aggregation:
instance of dataset
availability:
available
primaryPublications: 6085200
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1009756
landingPage: http://www.iedb.org/assay/1482481
type:
Literature
publicationVenue:
Virus Res
dates:
1984
study type: b cell assays
subject species: Foot-and-mouth disease virus (strain A12)
fullName:
B H Robertson
D O Morgan
D M Moore
method:
biological activity
name:
Location of neutralizing epitopes defined by monoclonal antibodies generated against the outer capsid polypeptide, VP1, of foot-and-mouth disease virus A12.
description:
The epitope sequence is from the reference cited: Robertson et al. (1983) J Virol 46: 311-316 [PMID: 6186823]. The epitope sequence was deduced.
The epitope-specific mAbs 7SF3 and 6HE4 neutralized the virus and bound the 140S virus particles and 12S subunits.

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