Delineation of a neutralizing subregion within the immunodominant epitope (GH loop) of foot-and-mouth disease virus VP1 which does not contain the RGD motif.

Title:

Delineation of a neutralizing subregion within the immunodominant epitope (GH loop) of foot-and-mouth disease virus VP1 which does not contain the RGD motif.

Dataset

identifier:	1482572
description:	epitope description:RYNRNAVPNL antigen name:Polyprotein host organism:Cavia porcellus
aggregation:	instance of dataset
availability:	available
primaryPublications:	10501234

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1008115
landingPage:	http://www.iedb.org/assay/1482572

Publication

type:	Literature
publicationVenue:	Vaccine
dates:	1999

Dimension

study type:	b cell assays
subject species:	Foot-and-mouth disease virus (strain O1)

Person

fullName:	F Brown N Benkirane D Limal H Halimi J F Newman M H Van Regenmortel J P Briand S Muller

Data Type

method:	antigen inhibition

Study

name:	Delineation of a neutralizing subregion within the immunodominant epitope (GH loop) of foot-and-mouth disease virus VP1 which does not contain the RGD motif.
description:	The epitope competed with VP1 sequence RYNRNAVPNLRGDLQVLAQKVARTL (residues 135-159) of FMDV type O1 for binding to the antisera.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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