New approach for generation of neutralizing antibody against human T-cell leukaemia virus type-I (HTLV-I) using phage clones.

Title:

New approach for generation of neutralizing antibody against human T-cell leukaemia virus type-I (HTLV-I) using phage clones.

identifier:	1482857
description:	epitope description:LPHSNL antigen name:Envelope glycoprotein gp62 host organism:Rattus norvegicus antibody name:LAT-27
aggregation:	instance of dataset
availability:	available
primaryPublications:	11818146

study type:	b cell assays
subject species:	Human T-lymphotropic virus 1

fullName:	Nurjahan Begum Sankichi Horiuchi Yuetsu Tanaka Norio Yamamoto Kouji Ichiyama Naoki Yamamoto

method:	antigen inhibition

name:	New approach for generation of neutralizing antibody against human T-cell leukaemia virus type-I (HTLV-I) using phage clones.
description:	The epitope-specific mAb was able to bind to phage clones L4-2-11, L4-2-22 and L4-1-22 that displayed the epitope, and the phage clones were able to compete for binding of the mAb to the peptide LPHSNLDHIL . Binding of the mAb to a fusion protein from the phage clones was also shown by Western blotting.

name:	iedb
homePage:	http://www.iedb.org

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