| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1006303 |
| landingPage: |
http://www.iedb.org/assay/1485883 |
| type: |
Literature
|
| publicationVenue: |
J Clin Virol
|
| dates: |
1998
|
| study type: | b cell assays |
| subject species: | Human respiratory syncytial virus A2 |
| fullName: |
I V Leonova
S V Leonov
M Waris
J C Russi
M Grandien
E Norrby
|
| method: |
ELISA
|
| name: |
Development of human antibodies against linear antigenic and immunogenic regions of respiratory syncytial virus (RSV) nucleocapsid and phospho-proteins shows the site-directed characteristics.
|
| description: |
The sequence source for the epitope was provided in Leonov et al. J Gen Virol 1994
75 :1353 [PMID: 8207401] as RSV A2.
The highest titers were observed against this epitope. The rise in IgG specific anti-P immune response could be non-correlative with the rise in the total specific anti-RSV immune response during primary or secondary infection. Approximately 58% of the variation in total anti-RSV titers in the late convalescent phase of infection may be predicted, given the initial titer of antibodies directed to the C-terminal major antigenic and immunogenic region of the RSV P protein represented by P62 peptide.
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |