Immunological Data Discovery Index
Immunological Data Discovery Index
| Title: | Identification of a T-cell epitope adjacent to neutralization antigenic site 1 of poliovirus type 1. |
| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1008274 |
| landingPage: |
http://www.iedb.org/assay/1486527 |
| type: |
Literature
|
| publicationVenue: |
J Virol
|
| dates: |
1991
|
| study type: | b cell assays |
| subject species: | Human poliovirus 1 Mahoney |
| fullName: |
C Leclerc
E Deriaud
V Mimic
S van der Werf
|
| method: |
biological activity
|
| name: |
Identification of a T-cell epitope adjacent to neutralization antigenic site 1 of poliovirus type 1.
|
| description: |
The epitope was synthesized with Gly-Cys residues at the C-terminus.
Four of 5 BALB/c mice immunized with the epitope developed virus neutralizing antibodies as determined by a plaque reduction assay. The serum of all 5 mice reacted with infectious (D particles) or heat-treated (C particles) virions by immunoprecipitation.
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| name: |
iedb
|
| homePage: |
http://www.iedb.org |