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Title: Native-like cyclic peptide models of a viral antigenic site: finding a balance between rigidity and flexibility.
identifier: 1483975
description:
epitope description:YTASARGDLAHLTTTHARHLP
antigen name:Polyprotein
host organism:Mus musculus BALB/c
antibody name:SD6
aggregation:
instance of dataset
availability:
available
primaryPublications: 10679891
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1011889
landingPage: http://www.iedb.org/assay/1483975
type:
Literature
publicationVenue:
J Mol Recognit
dates:
2000
study type: b cell assays
subject species: Foot-and-mouth disease virus C-S8c1
fullName:
M L Valero
J A Camarero
M G Mateu
E Domingo
E Giralt
D Andreu
method:
surface plasmon resonance (SPR)
name:
Native-like cyclic peptide models of a viral antigenic site: finding a balance between rigidity and flexibility.
description:
Cys residue was added at C-terminus.
Internal disulfide cyclization resulted in one to two orders of magnitude better recognition than to the linear peptide. The cyclic peptide was stabilized by the disulfide cyclization determined with CD and NMR structural analysis.

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