Immunological Data Discovery Index
Immunological Data Discovery Index
| authorizations: |
registration not required
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| accessURL: |
http://www.iedb.org/reference/1006309 |
| landingPage: |
http://www.iedb.org/assay/1484097 |
| type: |
Literature
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| publicationVenue: |
J Virol
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| dates: |
1997
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| study type: | b cell assays |
| subject species: | Measles virus strain Edmonston |
| fullName: |
S F Atabani
O E Obeid
D Chargelegue
P Aaby
H Whittle
M W Steward
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| method: |
ELISA
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| name: |
Identification of an immunodominant neutralizing and protective epitope from measles virus fusion protein by using human sera from acute infection.
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| description: |
All of the 18 human serum samples reacted with the peptide. The mean titers against this epitope were 1/3,200. Fine mapping studies showed that the 15-mer epitope was the minimal/optimal peptide for human sera. Moreover, reactivity with the epitope was abolished if the cysteine residues [C390, C395 and C397] were replaced with serine residues. This sequence is conserved in all morbilliviruses.
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| name: |
iedb
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| homePage: |
http://www.iedb.org |
