Identification of group-common linear epitopes in structural and nonstructural proteins of enteroviruses by using synthetic peptides.

Title:

Identification of group-common linear epitopes in structural and nonstructural proteins of enteroviruses by using synthetic peptides.

identifier:	1483643
description:	epitope description:PALTAAETG antigen name:Genome polyprotein host organism:Homo sapiens
aggregation:	instance of dataset
availability:	available
primaryPublications:	7681848

study type:	b cell assays
subject species:	Coxsackievirus B3

fullName:	J Cello A Samuelson P Stå lhandske B Svennerholm S Jeansson M Forsgren

method:	antigen inhibition

name:	Identification of group-common linear epitopes in structural and nonstructural proteins of enteroviruses by using synthetic peptides.
description:	The epitope was synthesized with an N-terminal Cys residue. The epitope sequence is conserved among enteroviruses and the source organism was arbitrarily assigned. Absorption of epitope-reactive patient sera with the epitope decreased the antibody titer fourfold against the epitope and the homologouus E1 peptide PALTAVETGATNPL. The authors conclude that E1 and E2 contain the same epitope.

name:	iedb
homePage:	http://www.iedb.org

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