Crossreactivity of mimotopes and peptide homologues of a sequential epitope with a monoclonal antibody does not predict crossreactive immunogenicity.

Title:

Crossreactivity of mimotopes and peptide homologues of a sequential epitope with a monoclonal antibody does not predict crossreactive immunogenicity.

Dataset

identifier:	1483719
description:	epitope description:SEMPQLPSEMPQLP host organism:Mus musculus BALB/c antibody name:Mouse sera
aggregation:	instance of dataset
availability:	available
primaryPublications:	10506653

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1008583
landingPage:	http://www.iedb.org/assay/1483719

Publication

type:	Literature
publicationVenue:	Vaccine
dates:	1999

Dimension

study type:	b cell assays
subject species:

Person

fullName:	K C El Kasmi S Deroo D M Theisen N H Brons C P Muller

Data Type

method:	ELISA

Study

name:	Crossreactivity of mimotopes and peptide homologues of a sequential epitope with a monoclonal antibody does not predict crossreactive immunogenicity.
description:	Sera from mice immunized with T2T2Mb7Mb7 reacted with a different mimotope of the wild-type B7 peptide. The Ma7 epitope was co-linearly synthesized with two copies of the T cell epitope T1 (MV F421-435). A GSGG spacer was inserted between the T and B cell moieties.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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