Lipopeptide immunization without adjuvant induces potent and long-lasting B, T helper, and cytotoxic T lymphocyte responses against a malaria liver stage antigen in mice and chimpanzees.

Title:

Lipopeptide immunization without adjuvant induces potent and long-lasting B, T helper, and cytotoxic T lymphocyte responses against a malaria liver stage antigen in mice and chimpanzees.

Dataset

identifier:	1485052
description:	epitope description:LEESQVNDDIFNSLVKSVQQEQQHNV antigen name:Liver stage antigen 3 host organism:Mus musculus SJL antibody name:Mouse sera
aggregation:	instance of dataset
availability:	available
primaryPublications:	9174617

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1012211
landingPage:	http://www.iedb.org/assay/1485052

Publication

type:	Literature
publicationVenue:	Eur J Immunol
dates:	1997

Dimension

study type:	b cell assays
subject species:	Plasmodium falciparum T9/96

Person

fullName:	L BenMohamed H Gras-Masse A P Daubersies K Brahimi M Bossus A P Druilhe

Data Type

method:	ELISA

Study

name:	Lipopeptide immunization without adjuvant induces potent and long-lasting B, T helper, and cytotoxic T lymphocyte responses against a malaria liver stage antigen in mice and chimpanzees.
description:	Immunization using a non-lipopeptide version of the epitope induced only very moderate titers in this mouse strain. By contrast, he lipopeptide immunogen (epitope linked to palmitoyl) induced high titers.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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